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USP L41_Esomeprazole

관리자 | 2014.07.17 16:03 | 조회 3820

 



Esomeprazole is a proton pump inhibitor (brand name Nexium, Essocam, Esomezol) which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells. By inhibiting the functioning of this transporter, the drug prevents formation of gastric acid.

It is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.

Esomeprazole is the S-enantiomer of omeprazole (brand name Prilosec/Losec). A generic version of esomeprazole strontium is available in the United States. Generic versions of esomeprazole magnesium are available in several countries of Europe and in emerging markets such as Pakistan, India, Peru, Ecuador, Caribbean Islands, Nigeria, Africa, Sri Lanka, Cambodia, and Myanmar under the brand name Raciper. In Bangladesh, esomeprazole is sold under the brand name Opton by Beximco Pharma, Neptor by Sandoz Bangladesh. In South Africa, it is available generically, as Nexmezol.[1] It is available over-the-counter under the brand name Nexium in the United States.

 

 

L41

Immobilized alfa1-acid glycoprotein on spherical silica particles, 5 µm in diameter.

Chiral AGP

1

Esomeprazole Magnesium

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